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Scientist found new powerful way to combat flu viruses

scientist-found-new-approach-to-attack-flu-virus

International research team has manufactured a new protein that can combat deadly flu epidemics. Scientists used manufactured genes as antivirals, which disable key functions of the flu virus. The most potent design has proven effective on the vulnerable sites on many pandemic influenza viruses, including several H1N1 (Spanish flu, Swine flu) and H5N1 (Avian flu) subtypes. It neutralizes H1N1 viruses with potency.

From its earlier research, the team used computer-aided design to engineer proteins that targeted vulnerable sites on the highly adaptable virus. From there, researchers optimized their designer proteins by comprehensively mapping the mutations that gave the proteins a strong advantage when attacking the viruses' targeted areas. The team improved their proteins through a process called "DNA deep sequencing." This allowed researchers to simultaneously sequence millions of variants of their manufactured proteins, identify and keep the beneficial mutations and optimize the proteins' performance.


By taking only the best mutations, scientists can reprogram our proteins to burrow into viruses at key locations and render them harmless. Their work demonstrates a new approach to construct therapeutic proteins, which they hope will spur development of new protein drugs by the biopharmaceutical industry. This research also laid the groundwork for future treatments of all flu viruses as well as other diseases such as smallpox.

Tim Whitehead, assistant professor of chemical engineering and materials science at Michigan State University is co-author of paper. Co-authors included researchers from the University of Washington, the Scripps Research Institute (La Jolla, Calif.), Naval Health Research Center (San Diego) and the Weizmann Institute of Science (Rehovot, Israel). The research was funded by Defense Research Projects Agency, the Defense Threat Reduction Agency, the National Institutes of Health, the National Institute of Allergy and Infectious Diseases and the National Institute of General Medical Sciences.

Nature Biotechnology paper

Source: MSU

Featured image: WoWT

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5 Comments

  1. Proteins? You certainly don’t want to feed the viruses protein. The duel shell that covers most all viruses, you guessed it. PROTEIN.! Basicly a virus is mainly all acid and acid is basicly Hydrogen atoms, Acids attack heavy metals, and B-12 is 5% Cobalt, which converts the Virus to H2o.

  2. What gets me is the medical Industrial Complex, which is a 8 trillion dollar operation,a year, really never seems to find a cure, but only by prescription Drugs. If they could make Aspirin a prescription,drug, they would.

    A CURE for Peptic Ulcers, which is basically caused by the H pylori bacteria, in the body, is a non prescription drug, which they weren’t happy about. The cure for it is Bismuth Subsalicylate, You might know it as Pepto Bismo. So what does the Drug industry do, The add two antibiotics to it, so the can sell it to you for 80 dollars, instead of 3.25 cents, plus give you the problem of the antibiotics they added.

    Now let’s get on to the Flu, and even the cold, they say there is no cure, garbage, if there is a cure, would this industry ever would want to give it to you and loose al that doctoring and drug business, of course not. Well there is a Cure for that, a very simple Cure. It seems they don’t like you to use that word “CURE”, will sue me, I dare you!

    If you go to http://www.popsci.com/node/22953 you will see a article on the CURE for the World’s Deadly Diseases, with 55 comments. The Cure is Vitamin Nasal B-12, which you have to put together, for it isn’t on the market, I wonder why?

    Now why does this work, A 5 year old could figure it out, if they just see the picture of a Flu Virus and a picture of Vitamin B-12 structure. Viruses are basically Acid. The flu virus has a double shell of protein, and a nuclic acid center, well what is protein, but Amino acids, and what is acid, but mainly Hydrogen monocules. Now if you look at a picture of the structure of Vitamin B-12 medical name, Cyanocobalamin, and right in the center of the structure of B-12, is Cobalt. which is a heavy metal. Now what does acids do to heavy metals, why they attack them, for that is what Hydrogen does. Now why does Hydrogen attack everything, because it only has one electron revolving around it where all the other elements have two or more and it wants to get married.

    To explain this, just look at a car battery. You have sulfuric acid in it and lead or cobalt plates, what makes your electricity is the sulfuric acid attacking the lead plates and in your body it creates Bio-electricity, and converts the Virus to H2O, Water.

    Now why it seems that the medical profession can’t cure the flu or Cold by injection is that the cells that line the respiratory track ARE NOT BASICALLY BATHED IN THE BLOOD STREAM. Simple.

    Now what do you do, you snort it up the nose, which will cover the virus and the virus will attack the B-12. If you put B-12 cures the Flu in your browser, it will come up on over 2200 websites.

    What is interesting is now there is a newer form of B-12, that was not discovered or developed in the U.S. but in Japan, probably today over 70 percent of the drugs developed are not in the U.S. but in foreign countries, and license to the drug companies in the U.S.

    The new form of Vitamin B-12 is called Methylcobalamin. this is developed, when the B-12 is passed through the liver. However when you take it, it doesn’t have to pass through the liver, but goes directly into the blood. I find it is very powerful in a fairly strong form, and probably could destroy a lot of cancers and also kill a lot of viruses. The only side effect from B-12 I find is it can make you a little hungry.

    I find that the goal of medicine should be to make the world a drug free and disease World. Not what it is today. There is no such Disease, that there is no Cure.

  3. I’m surprised that this article does not suggest or really even hint at how it is supposed that these engineered proteins will be administered where needed, or how this mechanism might be expressed in the human body. Can anyone shed some light here? Thanks.

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